They tested it on various Android devices, including standard Nokia, Huawei, LG and Sony models. They tested the Genopo app on the raw sequencing data of virus samples isolated from nine Covid-19 patients in Sydney and sequenced with a MinION nanopore device. The app combines several available bioinformatics tools into a single app, 'miniaturised' to work on the processing power of a typical consumer Android phone. The researchers – collaborating with engineers from Sri Lanka’s University of Peradeniya – developed an app which could execute bioinformatics workflows on genetic datasets downloaded to a smartphone, adapting to the resource constraints in smartphones. We set out to change that,” said co-senior author Hasindu Gamaarachichi, a computer engineer at the Garvan Institute. “Until now, genomic analysis has required the processing power of high-end server computers or cloud services. “Our app makes genomic analysis more accessible, literally placing the technology into the pockets of scientists around the world.”ĭuring genome sequence analysis, the strings of genetic code from raw data are pieced together into a single sequence, from which genetic variations indicating viral mutation can be identified. “Fast, real-time genomic analysis is more crucial today than ever, as a central method for tracking the spread of coronavirus. “Not everyone has access to the high-power computing resources that are required for DNA and RNA analysis, but most people have access to a smartphone,” said the Garvan Institute’s Ira Deveson, co-senior author of the Communications Biology paper describing the project. During Ebola surveillance in West Africa, for instance, field research was disrupted by internet connectivity issues in which they were forced to slowly upload large datasets via 2G for analysis elsewhere. At present, analysis of these data requires access to high-end computing power. However, advances in in situ genomics will require the parallel development of portable, offline tools to analyse the data gathered by these tools.
#Covid 19 genome sequence analysis portable#
Portable nanopore devices – which measure changes in current as a DNA or RNA strand passes through a nanopore – allow scientists and clinicians to sequence the genome of viruses such as the Covid-19 or Ebola viruses outside laboratory settings.
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